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Smart textiles with active antimicrobial activity


Abstract

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Description of Projectidea

Textiles and garments used in healthcare promote cross-infection as they are used as a vehicle by the pathogenic bacteria to spread infections. Multi-drug resistant disease-causing bacteria are not only critical for health care personnel and patients but are also problematic if spread to the environment and lead to further infections in a large number of persons. Smart materials with antimicrobial properties may assist in reducing (cross-) infections and transmission of infectious diseases. The stable coupling of short antimicrobial peptides (AMPs) to textile polymeric fibers shows biocidal activity against a broad spectrum of pathogenic organisms while being non-toxic to the consumer and environment. The Fraunhofer Institute for Cell Therapy and Immunology, Furthermore, short peptide binders can be generated to detect a specific pathogen. In a scaffold these structures can be combined with artificial signal-generating groups (sensor-actor molecules) indicating the presence of a particular dangerous organism.


Consortium of partners, already involved

The scientists at the Fraunhofer IZI-BB have vast experience in research and development projects which are close to a practical use. For the described project the existing competences may be of assistance:
- Anti-microbial peptides
- Different coupling strategies for antimicrobial peptides to while maintaining the biocidal function
- Tests for biocompatibility and effectiveness
- Work with pathogens according to the Protection against Infection Act of Safety Class 2, with regulatory authority approval to Class 3.
- Peptide synthesis, Surface and chemical characterization (IR, MS, Ellipsometer, HPLC,...)


Partners sought to complete the consortium

For the proposed projects cooperation partners in the following fields are sought:
- Manufacturers of textiles and garments for healthcare or other areas
- Partner for peptide synthesis
- Manufacturers who possess a modular or continuous production line for textile based material
- Fiber and textile technology
- ...


Topics

M-ERA.NET 2 - 2017:
Innovative surfaces, coatings and interfaces
 


Contact

Sebastian Kersting
 
Fraunhofer IZI-BB
 
Am Muehlenberg 13
14476 Potsdam
Germany
 
Homepage: http://https://www.izi.fraunhofer.de/
Email: sebastian.kersting@izi-bb.fraunhofer.de
Phone: 033158187214
Organisation: Research Organization

Responsible NCP

Dipl.-Ing. Jens Korell
Projektträger Karlsruhe - Produktion und Fertigungstechnologien (PTKA-PFT)
jens.korell@kit.edu
Telephone:+49 721 608-26527
Telefax:+49 721 608-25456
Germany